Archives of cardiovascular diseases · 2014
Percutaneous valvulation of failing Fontan: rationale, acute effects and follow-up.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
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Malekzadeh-Milani Sophie, Ladouceur Magalie, Iserin Laurence, Boudjemline Younes
Аннотация
BACKGROUND: Fontan circulation is fragile and unfavourable evolution is frequent. Fontan physiology largely depends on respiration and gravity. The hypothesis for valvulation is that valvulation of the circuit reduces the effects of respiration and the proclive position, and increases anterograde flow towards the systemic circulation, with increasing exercise capacity and benefits for enteropathy. Because it originates from the bovine jugular vein, the Melody(®) valve (Medtronic, Minneapolis, MN, USA) is naturally designed to work in a low-pressure environment.
AIMS: To report our experience of percutaneous valvulation of refractory failing Fontan circulation.
METHODS: We reviewed all patients who received a Melody valve in Fontan circulation in our unit.
RESULTS: Four patients were included: two had severe and refractory protein-losing enteropathy; one had severe oedema and ascites; and one had very severe lower limb venous insufficiency. The Melody valve was successfully implanted in all patients. Central venous pressure and inferior vena cava pressure did not change after valvulation. There were no early complications. At follow-up, no acute or mid-term thrombosis was noted. Two patients had intracardiac echocardiography 6 and 24 months after valvulation: the Melody valve was found not to be functioning in both cases. One patient died 3 months after valvulation; the cause was unrelated to the procedure.
CONCLUSION: Percutaneous valvulation of Fontan circulation is technically feasible. More clinical studies are needed before considering this treatment as an option.
AIMS: To report our experience of percutaneous valvulation of refractory failing Fontan circulation.
METHODS: We reviewed all patients who received a Melody valve in Fontan circulation in our unit.
RESULTS: Four patients were included: two had severe and refractory protein-losing enteropathy; one had severe oedema and ascites; and one had very severe lower limb venous insufficiency. The Melody valve was successfully implanted in all patients. Central venous pressure and inferior vena cava pressure did not change after valvulation. There were no early complications. At follow-up, no acute or mid-term thrombosis was noted. Two patients had intracardiac echocardiography 6 and 24 months after valvulation: the Melody valve was found not to be functioning in both cases. One patient died 3 months after valvulation; the cause was unrelated to the procedure.
CONCLUSION: Percutaneous valvulation of Fontan circulation is technically feasible. More clinical studies are needed before considering this treatment as an option.