[Ethical Issues in Early Serological Diagnosis of Alzheimer's Disease].

UNLABELLED: The ethical conflicts involved in the medical indication of early serological diagnosis in Alzheimer's disease, for clinical contexts where a medical indication is required to perform the intervention, have been scarcely analyzed.

HYPOTHESIS: The prescription of early serological diagnosis in Alzheimer's disease violates more principles than it supports.

AIM: To carry out an analysis regarding the ethical conflicts associated with the indication of early serological diagnosis of Alzheimer's disease and to offer a clinical practice recommendation based on said analysis.

METHODS

Ethical analysis, in which the logical consequences of prescribing early serological diagnosis will be explained in terms of the ethical principles of autonomy, justice, beneficence and non-maleficence.

RESULTS

The intervention presents marginal benefit in terms of autonomy and beneficence, while it violates the principles of beneficence, non-maleficence and justice.

CONCLUSIONS

The intervention is not ethically recommended. This could change if its cost diminishes and if disease-modifying therapies with an adequate safety profile are developed.