Der Orthopade · 2010
[Preclinical evaluation of coated knee implants for allergic patients].
Аннотация на английскомСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Reich J, Hovy L, Lindenmaier H-L, Zeller R, Schwiesau J, Thomas P, Grupp T M
Аннотация
BACKGROUND: 10-15% of the population show allergic reactions against skin contact to metals as nickel, cobalt or chromium and have thus a risk of not tolerating implants containing those materials. The relationship between periimplantary hypersensivity reaction and given cutaneous contact allergy is currently unknown. A new developed multilayer coating system is supposed to prevent long-term allergic reactions that may result from uncoated implants.
METHODS: Stability and function (concerning bonding durability, wear and ion release to the serum) of the multilayer coating system has been examined in a test series.
RESULTS: The specific architecture of the multilayer coating system evidences a very good bonding durability. The results of the test in the simulator show a reduction of wear of approximately 60% compared to the uncoated implants. Ion concentrations within the serum of the wear tests were by magnitudes lower than those measured in reference tests on uncoated components.
CONCLUSION: The results of the preclinical evaluation prove that the durability and function of the multilayer coating system are as intended.
METHODS: Stability and function (concerning bonding durability, wear and ion release to the serum) of the multilayer coating system has been examined in a test series.
RESULTS: The specific architecture of the multilayer coating system evidences a very good bonding durability. The results of the test in the simulator show a reduction of wear of approximately 60% compared to the uncoated implants. Ion concentrations within the serum of the wear tests were by magnitudes lower than those measured in reference tests on uncoated components.
CONCLUSION: The results of the preclinical evaluation prove that the durability and function of the multilayer coating system are as intended.