Frontiers in veterinary science · 2026
Signalment, clinical characteristics, and echocardiographic findings in dogs affected by secondary atrial fibrillation with and without concomitant frequent and complex ventricular arrhythmias.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Romito Giovanni, Mazzoldi Chiara, Riccio Chiara, Fogli Marcello, Paradies Paola, Recchia Alessandra, Pelle Nazzareno Giuseppe, Testa Fabio, Valente Carlotta, Poser Helen, Arcuri Giulia, Contiero Barbara, Guglielmini Carlo
Аннотация
INTRODUCTION: Assessment of dogs with atrial fibrillation (AF) and ventricular arrhythmias (VAs), two arrhythmias that can coexist, is traditionally based on 24-h Holter monitoring. However, this test may not always be feasible. The aim of this study was to determine whether alternative methods exist to distinguish dogs affected by secondary AF with frequent and complex VAs from those without.
METHODS: In this multicenter retrospective study, electronic databases from five centers were searched for dogs with a diagnosis of secondary AF. For inclusion, complete clinical, echocardiographic and 24-h Holter data had to be available for each dog. Signalment, clinical, and echocardiographic variables of left cardiac dimension and function were compared between dogs with secondary AF exhibiting frequent ventricular premature complexes (VPCs; ≥100/Holter) or severe VAs (Lown-Wolf grade ≥4) and those without.
RESULTS: Fifty-nine dogs, including 35/59 (59.3%) dogs with myxomatous mitral valve disease, 17/59 (28.8%) dogs with dilated cardiomyopathy, and 7/59 (11.9%) dogs with congenital heart disease, were evaluated. Compensated and decompensated cardiac disease was diagnosed in 10/59 (16.9%) and 49/59 (83.1%) dogs, respectively. Holter monitoring detected VAs associated with AF in 58/59 (98.3%) dogs. Among dogs with VPCs, the median number of VPCs was 265 (1-1,759) and 32/59 (54.2%) dogs had ≥100 VPCs/Holter. Regarding VA complexity, 34/59 (57.6%) dogs exhibited a Lown-Wolf grade ≥4. Statistical analyses revealed that none of the 17 analyzed variables reached significance in differentiating dogs with and without frequent VPCs, as well as dogs with and without complex VAs.
DISCUSSION: In dogs with secondary AF, VAs are usually present and are frequently of clinical relevance according to their Lown-Wolf grade. However, signalment, clinical presentation, and conventional echocardiographic data do not reliably distinguish dogs with frequent VPCs or complex VAs from those without, reinforcing the indispensable role of 24-h Holter monitoring for the accurate assessment of these subjects.
METHODS: In this multicenter retrospective study, electronic databases from five centers were searched for dogs with a diagnosis of secondary AF. For inclusion, complete clinical, echocardiographic and 24-h Holter data had to be available for each dog. Signalment, clinical, and echocardiographic variables of left cardiac dimension and function were compared between dogs with secondary AF exhibiting frequent ventricular premature complexes (VPCs; ≥100/Holter) or severe VAs (Lown-Wolf grade ≥4) and those without.
RESULTS: Fifty-nine dogs, including 35/59 (59.3%) dogs with myxomatous mitral valve disease, 17/59 (28.8%) dogs with dilated cardiomyopathy, and 7/59 (11.9%) dogs with congenital heart disease, were evaluated. Compensated and decompensated cardiac disease was diagnosed in 10/59 (16.9%) and 49/59 (83.1%) dogs, respectively. Holter monitoring detected VAs associated with AF in 58/59 (98.3%) dogs. Among dogs with VPCs, the median number of VPCs was 265 (1-1,759) and 32/59 (54.2%) dogs had ≥100 VPCs/Holter. Regarding VA complexity, 34/59 (57.6%) dogs exhibited a Lown-Wolf grade ≥4. Statistical analyses revealed that none of the 17 analyzed variables reached significance in differentiating dogs with and without frequent VPCs, as well as dogs with and without complex VAs.
DISCUSSION: In dogs with secondary AF, VAs are usually present and are frequently of clinical relevance according to their Lown-Wolf grade. However, signalment, clinical presentation, and conventional echocardiographic data do not reliably distinguish dogs with frequent VPCs or complex VAs from those without, reinforcing the indispensable role of 24-h Holter monitoring for the accurate assessment of these subjects.