[Creatine kinase activity in guinea pig tissues in experimental pseudotuberculosis].

Dynamics of creatine kinase activity was studied in heart muscle, liver tissue, lymphatic glands, intestine and spleen of guinea pigs infected with pseudotuberculosis microbes. The maximal increase in creatine kinase activity was observed in lymphatic glands and in heart muscle within the first day after the pseudotuberculosis infection. The enzymatic activity increase in liver tissue occurred within the fifth day, while in spleen--within twelfth day after pseudotuberculosis infection. The data obtained were considered in correlation with the clinical manifestations of experimental pseudotuberculosis.