The Journal of craniofacial surgery · 2014
Platelet-rich fibrin plays a role on healing of acute-traumatic ear drum perforation.
СтатьяРандомизированное исследованиеНазвание и аннотация: Перевод пока не подготовлен
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Habesoglu Mehmet, Oysu Cagatay, Sahin Serap, Sahin-Yilmaz Asli, Korkmaz Deniz, Tosun Ahmet, Karaaslan Ahmet
Аннотация
OBJECTIVE: Our objective was to demonstrate the effects of platelet-rich fibrin (PRF) for the healing of acute ear drum perforation.
METHODS: Thirty-two patients with acute traumatic ear drum perforations were randomly separated into 2 groups. In group 1 (n = 14), PRF was used for the repair of ear drum perforation; in group 2 (n = 18), we did not make any intervention.
RESULTS: At initial inspection, perforation sizes were measured as 10.93 ± 3.58 mm in group 1 and 10.05 ± 4.02 mm in group 2. After 1 month, perforation sizes were 1.35 ± 2.53 mm in group 1 and 4.44 ± 3.34 mm in group 2 (P < 0.01). In the study group, the rate of ear drum closure was 64.3% and in the control group it was 22.2% (P < 0.05).
CONCLUSION: Here we found that PRF is a biomaterial that quickens the healing of ear drum which is autogenous and simply prepared.
METHODS: Thirty-two patients with acute traumatic ear drum perforations were randomly separated into 2 groups. In group 1 (n = 14), PRF was used for the repair of ear drum perforation; in group 2 (n = 18), we did not make any intervention.
RESULTS: At initial inspection, perforation sizes were measured as 10.93 ± 3.58 mm in group 1 and 10.05 ± 4.02 mm in group 2. After 1 month, perforation sizes were 1.35 ± 2.53 mm in group 1 and 4.44 ± 3.34 mm in group 2 (P < 0.01). In the study group, the rate of ear drum closure was 64.3% and in the control group it was 22.2% (P < 0.05).
CONCLUSION: Here we found that PRF is a biomaterial that quickens the healing of ear drum which is autogenous and simply prepared.