Conversion of chronic gingivitis to periodontitis in squirrel monkeys.

1. Acute exacerbation of gingivitis can lead to destructive periodontitis. 2. Such periods of acute inflammation may be associated with epithelial ulceration. 3. Bone loss in periodontal disease may occur in bursts of osteoclastic activity triggered by cells or factors generated during an acute phase. 4. Partial repair can follow an acute episode and a "stable lesion" may become re-established.