The American journal of medicine · 2013
Sarcoidosis lung nodules in colorectal cancer follow-up: sarcoidosis or not?
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Lequoy Marie, Coriat Romain, Rouquette Alexandre, Mir Olivier, Perkins Géraldine, Regnard Jean-François, Brezault Catherine, Chaussade Stanislas
Аннотация
OBJECTIVE: Sarcoidosis is a multisystem chronic granulomatous disease found predominantly in the lungs and lymph nodes. Its pathologic hallmark is the presence of noncaseating granulomas. Sarcoidosis is a chronic inflammatory condition that may increase the risk of cancer, yet at the same time, cancer can be associated with a sarcoid-like reaction.
METHODS: It is difficult to distinguish between sarcoidosis and sarcoid-like reactions because their imaging characteristics are identical. We report on 3 cases of sarcoidosis or sarcoid-like reactions in patients with colorectal cancer and highlight the diagnosis process.
RESULTS: Systemic symptoms observed in patients with sarcoidosis commonly can be masked or mimicked by symptoms related to the malignancy. Moreover, it is important to distinguish between the 2 entities to give patients adequate therapy.
CONCLUSION: Our cases focused on the usefulness of histologic proof in patients with cancer with sarcoidosis.
METHODS: It is difficult to distinguish between sarcoidosis and sarcoid-like reactions because their imaging characteristics are identical. We report on 3 cases of sarcoidosis or sarcoid-like reactions in patients with colorectal cancer and highlight the diagnosis process.
RESULTS: Systemic symptoms observed in patients with sarcoidosis commonly can be masked or mimicked by symptoms related to the malignancy. Moreover, it is important to distinguish between the 2 entities to give patients adequate therapy.
CONCLUSION: Our cases focused on the usefulness of histologic proof in patients with cancer with sarcoidosis.