Microbiological assessment of silver nanoparticles versus minocycline.

Evaluation of 0.02% silver nanoparticle (AGNP) gel and 2% minocycline gel as adjuncts to scaling and roots planning (SRP) in chronic periodontitis is of interest. Hence, 30 patients with 90 sites were divided into three groups: SRP alone, SRP + AGNP and SRP + minocycline. Clinical parameters improved significantly in all groups at 3 months (p < 0.001). AGNP and minocycline showed superior outcomes to SRP alone, with no significant difference between them. Thus, AGNP gel is as effective as minocycline and may serve as a promising adjunctive therapy.