Journal of pharmacy & bioallied sciences · 2025
Assessment of Low Level Laser Therapy on Periodontal Inflammation and Healing after Scaling and Root Planing in Chronic Periodontitis Patients - A Clinico Biochemical Study.
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Soni Rakhi, Sharma Mimoh, Tabassum, Singh Renu, Yadav Bipin K, Thakur Rajesh K
Аннотация
AIM: The aim of this study was to determine how Low-level laser therapy (LLLT) post- Scaling and root planning (SRP) affected the inflammatory periodontal tissue caused by chronic periodontitis.
METHODOLOGY: The study involved 56 sites in 28 patients with almost bilaterally symmetrical moderate pocket depths. The sites were split into two groups at random. SRP was administered alone to Group I, while SRP with LLLT were administered to Group II. In addition to recording the clinical parameters [plaque index (PI), sulcus bleeding index (SBI), and probing pocket depth (PPD)], GCF sample was taken at baseline, 3 to 4 weeks, and 6 to 7 weeks from baseline. The visual analogue scale (VAS) was scored for both groups on the final day of LLLT, which was 7 days following SRP. All GCF samples were then sent for TGF-β1 and PGE2 biochemical analysis.
RESULTS: This study demonstrated a significant reduction in PI, SBI, PPD, VAS score, PGE2 and TGF- β1 level in GCF in group I after SRP. Similarly in group II, which received LLLT with SRP, showed a significant decrease in all clinical and biochemical parameters. Intergroup comparison showed no significant difference in PI, SBI, TGF-β1 levels in the GCF. However, there was a significant difference in PPD, VAS score, and PGE2 level results.
CONCLUSION: Our study concluded that LLLT may be effective in reducing inflammation when used as an adjunct to SRP.
METHODOLOGY: The study involved 56 sites in 28 patients with almost bilaterally symmetrical moderate pocket depths. The sites were split into two groups at random. SRP was administered alone to Group I, while SRP with LLLT were administered to Group II. In addition to recording the clinical parameters [plaque index (PI), sulcus bleeding index (SBI), and probing pocket depth (PPD)], GCF sample was taken at baseline, 3 to 4 weeks, and 6 to 7 weeks from baseline. The visual analogue scale (VAS) was scored for both groups on the final day of LLLT, which was 7 days following SRP. All GCF samples were then sent for TGF-β1 and PGE2 biochemical analysis.
RESULTS: This study demonstrated a significant reduction in PI, SBI, PPD, VAS score, PGE2 and TGF- β1 level in GCF in group I after SRP. Similarly in group II, which received LLLT with SRP, showed a significant decrease in all clinical and biochemical parameters. Intergroup comparison showed no significant difference in PI, SBI, TGF-β1 levels in the GCF. However, there was a significant difference in PPD, VAS score, and PGE2 level results.
CONCLUSION: Our study concluded that LLLT may be effective in reducing inflammation when used as an adjunct to SRP.