Journal of pharmacy & bioallied sciences · 2024
Efficacy of Olive Oil, Ozonated Olive Oil, and Chlorhexidine Gel as an Adjunct to Scaling and Root Planing in Chronic Periodontitis: A Clinical Study.
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Mukherjee Koushik, Amaranath Bj Janardhana, Das Neelam, Dhanai Anishka, Pallavi Kumari, Katiyar Priya
Аннотация
OBJECTIVES: The aim of this article is to evaluate and compare the efficacy of subgingival application of ozonated olive oil, plain olive oil, and chlorhexidine gel as an adjunct to scaling and root planing (SRP) in chronic periodontitis.
MATERIALS AND METHODS: One hundred and twenty patients with chronic periodontitis were included in this study and assigned into three groups. In Group I, Group II, and Group III, SRP was done followed by subgingival application of ozonated olive oil, plain olive oil, and chlorhexidine gel in Group I, II, and III, respectively, at baseline 7, 14, and 21 days. Recordings of clinical parameters (gingival index [GI], probing pocket depth [PPD], clinical attachment level [CAL]) were done at baseline and one month.
RESULTS: The mean GI, PPD, and CAL scores at baseline for Group I was 2.78 ± 0.42, 2.78 ± 0.42, and 2.66 ± 0.38; for Group II was 2.64 ± 0.39, 6.40 ± 0.50, and 6.40 ± 0.50; and for Group III was 6.00 ± 0.00, 6.40 ± 0.50, and 6.40 ± 0.50, and the scores after one month for Group I was 1.10 ± 0.38, 0.21 ± 0.07, and 0.07 ± 0.05; for Group II was 0.05 ± 0.05, 5.40 ± 0.50, and 5.75 ± 0.44; and for Group III was 5.00 ± 0.00, 5.75 ± 0.44, and 5.28 ± 0.45, with the level of significance being (P < 0.001).
CONCLUSION: The ozonated olive oil and chlorhexidine gel have shown significant improvement in periodontal health compared to plain olive oil. Ozonated olive oil can be used as local drug delivery (LDD), an adjunct to SRP in chronic periodontitis which is safe and well accepted by patients without any noticeable side effects.
MATERIALS AND METHODS: One hundred and twenty patients with chronic periodontitis were included in this study and assigned into three groups. In Group I, Group II, and Group III, SRP was done followed by subgingival application of ozonated olive oil, plain olive oil, and chlorhexidine gel in Group I, II, and III, respectively, at baseline 7, 14, and 21 days. Recordings of clinical parameters (gingival index [GI], probing pocket depth [PPD], clinical attachment level [CAL]) were done at baseline and one month.
RESULTS: The mean GI, PPD, and CAL scores at baseline for Group I was 2.78 ± 0.42, 2.78 ± 0.42, and 2.66 ± 0.38; for Group II was 2.64 ± 0.39, 6.40 ± 0.50, and 6.40 ± 0.50; and for Group III was 6.00 ± 0.00, 6.40 ± 0.50, and 6.40 ± 0.50, and the scores after one month for Group I was 1.10 ± 0.38, 0.21 ± 0.07, and 0.07 ± 0.05; for Group II was 0.05 ± 0.05, 5.40 ± 0.50, and 5.75 ± 0.44; and for Group III was 5.00 ± 0.00, 5.75 ± 0.44, and 5.28 ± 0.45, with the level of significance being (P < 0.001).
CONCLUSION: The ozonated olive oil and chlorhexidine gel have shown significant improvement in periodontal health compared to plain olive oil. Ozonated olive oil can be used as local drug delivery (LDD), an adjunct to SRP in chronic periodontitis which is safe and well accepted by patients without any noticeable side effects.