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Cardiology research · 2025

Heart Conditioning as a Healthy Strategy in Management of Cardiac Enlargement.

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Lee David Wing-Ching, Lee William Wing-Ho, Lee Andrew Ying-Siu

Аннотация

BACKGROUND: Remote ischemic conditioning (RIC) is widely recognized for its cardioprotective effects in the context of ischemic heart disease. Lately, it has been shown that heart conditioning can be utilized as a healthy strategy in the reversion of disease and aging. In this regard, we examine the impact of RIC on patients with cardiac enlargement.

METHODS: Forty-four patients with cardiac enlargement were prospectively enrolled and randomly assigned into RIC group (n = 22) and control group (n = 22). RIC protocol is 3-min inflation/deflation of the blood pressure cuff applied in the upper arm to create transient arm ischemia. RIC treatment was performed once a day for 1 year. Left atrial and ventricular dimensions and left ventricular ejection fraction (LVEF) were all assessed in two groups.

RESULTS: RIC was well-tolerated. After 1 year treatment, left atrial and ventricular dimensions were significantly decreased in the RIC group. Moreover, LVEF showed a significant increase, from 46.24% to 56.45% (P < 0.0001).

CONCLUSION: The research indicates that a year-long healthy regimen of RIC treatment may effectively reverse cardiac enlargement, thereby endorsing the broader implementation of RIC in the daily routines of these patients.

ИП Урсолов Владлен Сергеевич

ИНН 500118482352 · ОГРНИП 314500117700049

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