Influence of dual vitamin D therapy on the outcome in patients with moderate-to-severe acute anterior circulation cerebral infarction and vitamin D insufficiency.

OBJECTIVE

To observe whether dual vitamin D supplementation therapy can improve the prognosis of patients with moderate-to-severe anterior circulation acute cerebral infarction accompanied by vitamin D deficiency.

METHODS

A retrospective analysis was conducted on 36 patients with moderate-to-severe anterior circulation acute cerebral infarction accompanied by vitamin D deficiency. They were divided into a dual vitamin D supplementation therapy group and a control group. The 90-day mRS scores of the two groups of patients and the occurrence of hypercalcemia were compared.

RESULTS

The difference in the number of mRS 0-3 cases at 90 days was statistically higher in the dual vitamin D supplementation group than in the control group (P < 0.05). No hypercalcemia was observed in either group.

CONCLUSION

Dual vitamin D supplementation improves outcomes in patients with moderate-to-severe anterior circulation acute cerebral infarction accompanied by vitamin D deficiency, and is relatively safe.