Current opinion in cardiology · 2006
Heart transplantation for end-stage valvular disease: indications and results.
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Pavie Alain
Аннотация
PURPOSE OF REVIEW: The aim of this study is to appraise the indications of a small group of heart transplanted patients with valvular disease, to analyse both their particular issues and results compared with the etiologies of other transplanted patients.
RECENT FINDINGS: Analysis of recent data shows that valvular patients represent between 3 and 5% of transplantation indications. This proportion of valvular patients had a tendency to decrease in many countries. These patients on the whole have undergone multiple reoperations. Pulmonary resistance analysis has to be especially rigorous for this group. A primary excess mortality is directly related to multiple reoperations. Mean and long-term results are then strictly comparable with other etiologies. There are a few very specific indications for recurrent endocarditis in this group.
SUMMARY: Valvular patients represent a subgroup of transplanted patients with a slight primary excess mortality but with identical long-term results.
RECENT FINDINGS: Analysis of recent data shows that valvular patients represent between 3 and 5% of transplantation indications. This proportion of valvular patients had a tendency to decrease in many countries. These patients on the whole have undergone multiple reoperations. Pulmonary resistance analysis has to be especially rigorous for this group. A primary excess mortality is directly related to multiple reoperations. Mean and long-term results are then strictly comparable with other etiologies. There are a few very specific indications for recurrent endocarditis in this group.
SUMMARY: Valvular patients represent a subgroup of transplanted patients with a slight primary excess mortality but with identical long-term results.