Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2025
Cardiac sarcoidosis recurrence post-heart transplant: A critical literature and case report.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
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Salotti Andrea, Mondini Lucrezia, Confalonieri Paola, Salton Francesco, Nalli Chiara, Reccardini Nicolò, Torregiani Chiara, Antonaglia Caterina, Hughes Michael, Confalonieri Marco, Cifaldi Rossella, Ruaro Barbara
Аннотация
BACKGROUND AND AIM: Recurrence of cardiac sarcoidosis (CS) following heart transplantation (HT) is a rare but clinically significant complication that influences management strategies and prognosis. This review examines existing evidence on the diagnosis and treatment of post-transplant CS recurrence. Additionally, we present a case report of CS recurrence in a patient after HT.
METHODS: We analyzed clinical studies, case reports, and systematic reviews published up to January 2025, focusing on the recurrence of CS after transplantation.
RESULTS: Limited data suggest that immunosuppressive therapies are crucial in managing post-transplant CS recurrence. Diagnosis relies on imaging modalities such as Positron Emission Tomography (PET-CT), Cardiac Magnetic Resonance (CMR), and endomyocardial biopsies. Treatment generally involves intensifying immunosuppressive therapy.
CONCLUSIONS: Standardized guidelines are essential to improve the management of this rare and complex condition and to enhance long-term patient outcomes.
METHODS: We analyzed clinical studies, case reports, and systematic reviews published up to January 2025, focusing on the recurrence of CS after transplantation.
RESULTS: Limited data suggest that immunosuppressive therapies are crucial in managing post-transplant CS recurrence. Diagnosis relies on imaging modalities such as Positron Emission Tomography (PET-CT), Cardiac Magnetic Resonance (CMR), and endomyocardial biopsies. Treatment generally involves intensifying immunosuppressive therapy.
CONCLUSIONS: Standardized guidelines are essential to improve the management of this rare and complex condition and to enhance long-term patient outcomes.