Immunocompromised Districts of Skin: A Case Series and a Literature Review.

BACKGROUND

The concept of immunocompromised districts of skin has been developed by Ruocco and helps to explain certain aspects of the macromorphology of skin diseases. This concept unites the isomorphic response of Koebner and the isotopic response of Wolf.

CASE REPORTS: We present different cutaneous conditions which can lead to immunocompromised districts of skin such as scars, radiodermatitis, lymphedema, disturbed innervation or mechanical friction etc. Typical and rarer skin disorders associated with them are discussed and illustrated by their observations.

CONCLUSION

At this moment, we wish to inform dermatologists and non-dermatologists about Ruocco's concept and its implications.