In vivo (Athens, Greece) · 2018
Clinical Advantage of Chest-wall Post-mastectomy Radiation Therapy Without Bolus.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Shiba Shintaro, Okamoto Masahiko, Kiyohara Hiroki, Okano Naoko, Yoshimoto Yuya, Murata Hiroto, Irie Daisuke, Katoh Hiroyuki, Nakano Takashi
Аннотация
BACKGROUND/AIM: The clinical outcomes of post-mastectomy radiation therapy (PMRT) without bolus remain to be fully examined, so that we evaluated clinical outcomes of PMRT without bolus and to measure the chest-wall dose surface histogram (DSH) parameters.
PATIENTS AND METHODS: Fifty-two patients with breast cancer who received PMRT without bolus were retrospectively analyzed. DSH values of the percentage of maximum dose (Dmax) were measured.
RESULTS: All patients completed the treatment; the median follow-up period was 22.1 months. The 2-year overall survival and local control rates were 85% and 95%. Five patients developed grade 2 acute radiation dermatitis, and none developed grade 2 or higher late radiation dermatitis. The median Dmax in patients who developed grade 0-1 and grade 2 acute radiation dermatitis was 5,178 and 5,365 cGy (p=0.03).
CONCLUSION: PMRT without bolus resulted in a low frequency of grade 2 or higher radiation dermatitis without increasing locoregional recurrences, and the Dmax was the contributing factor for developing acute radiation dermatitis.
PATIENTS AND METHODS: Fifty-two patients with breast cancer who received PMRT without bolus were retrospectively analyzed. DSH values of the percentage of maximum dose (Dmax) were measured.
RESULTS: All patients completed the treatment; the median follow-up period was 22.1 months. The 2-year overall survival and local control rates were 85% and 95%. Five patients developed grade 2 acute radiation dermatitis, and none developed grade 2 or higher late radiation dermatitis. The median Dmax in patients who developed grade 0-1 and grade 2 acute radiation dermatitis was 5,178 and 5,365 cGy (p=0.03).
CONCLUSION: PMRT without bolus resulted in a low frequency of grade 2 or higher radiation dermatitis without increasing locoregional recurrences, and the Dmax was the contributing factor for developing acute radiation dermatitis.