Content of Atrial Natriuretic Peptide in Cardiomyocytes Granules of Newborn Female Rats with Type 1 Diabetes Mellitus.

The intensity of accumulation and excretion of atrial natriuretic peptide (ANP) in right atrial myocytes of 1-day-old offspring born to female rats with streptozotocin-induced type 1 diabetes mellitus was studied using transmission electron microscopy and immunocytochemistry. The data indicate a reduced ANP content relative to the control group. No significant differences were found in the morphometric characteristics of the right atrium ultrastructure between the control and experimental groups.