Revista da Associacao Medica Brasileira (1992) · 2026
Evaluation of the use of dienogest in women with deep endometriosis and ovarian endometrioma: a retrospective cohort study.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Onishi Arissa, Leonardo-Pinto Joao Paulo, Benetti-Pinto Cristina Laguna, Yela Daniela Angerame
Аннотация
OBJECTIVE: The aim of this study was to evaluate the use of dienogest in the treatment of deep endometriosis and ovarian endometrioma.
METHODS: This retrospective cohort study included 59 women diagnosed with ovarian endometrioma at a tertiary hospital between 2013 and 2018. Pain scores and endometrioma size were evaluated after 12 months of dienogest use, along with the women's sociodemographic characteristics.
RESULTS: The mean age of the participants was 35.7±6.9 years. Unilateral endometrioma was observed in 38.9% of cases. There was a significant reduction in dysmenorrhea (p=0.011) with dienogest use, but no reduction in other pain symptoms. A reduction in left ovarian volume (p=0.009), mean left endometrioma size (p=0.01), and lesion size in the anterior cul-de-sac (p=0.047) was observed after dienogest treatment. A positive correlation was found between dyschezia and lesions in the posterior cul-de-sac before initiation of dienogest treatment.
CONCLUSION: Dienogest appears to reduce pain in women with deep endometriosis. Our findings support dienogest as an effective therapeutic option.
METHODS: This retrospective cohort study included 59 women diagnosed with ovarian endometrioma at a tertiary hospital between 2013 and 2018. Pain scores and endometrioma size were evaluated after 12 months of dienogest use, along with the women's sociodemographic characteristics.
RESULTS: The mean age of the participants was 35.7±6.9 years. Unilateral endometrioma was observed in 38.9% of cases. There was a significant reduction in dysmenorrhea (p=0.011) with dienogest use, but no reduction in other pain symptoms. A reduction in left ovarian volume (p=0.009), mean left endometrioma size (p=0.01), and lesion size in the anterior cul-de-sac (p=0.047) was observed after dienogest treatment. A positive correlation was found between dyschezia and lesions in the posterior cul-de-sac before initiation of dienogest treatment.
CONCLUSION: Dienogest appears to reduce pain in women with deep endometriosis. Our findings support dienogest as an effective therapeutic option.