[Prevention of adhesions. Wish and reality].

For more than a century peritoneal adhesions are being recognized as frequent sequelae following abdominal surgery. Intraoperative lesions of the mesothelial lining by abrasion, ischemia, dissication, and foreign bodies result in complaints, intestinal obstruction, female infertility, and problems during reoperations. The global increase of life expectancy and surgical procedures are leading to rising incidences of adhesion-related complications and subsequent socio-economic implications. As of today, there is no safe and efficient prophylaxis available. Scientific efforts should be aimed at a liquid substance for single intraperitoneal application which significantly reduces postoperative adhesions at reasonable cost without adverse effects on blood coagulation and wound healing.