The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2010
Otologic and audiologic outcomes with the Furlow and von Langenbeck with intravelar veloplasty palatoplasties in unilateral cleft lip and palate.
Сравнительное исследованиеСтатьяРандомизированное исследованиеПоддержка NIH: внешняя программаНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Antonelli Patrick J, Jorge José C, Feniman Mariza R, Piazentin-Penna Sílvia H A, Dutka-Souza Jeniffer C R, Seagle M Brent, Williams William N, Nackashi John A, Boggs Steve, Graciano Maria I G, Souza Telma V, Neto José S M, Garla Luis A, Silva Marcos L N, Marques Ilza L, Borgo Hilton C, Martinelli Angela P M C, Shuster Jonathan J, Pimentel Maria C M, Zimmermann Maria C, Bento-Gonçalves Cristina G A, Kemker F Joseph, McGorray Susan P, Pegoraro-Krook Maria I
Аннотация
OBJECTIVE: Cleft palate increases the risk of chronic middle ear disease and hearing loss. The goal of this report was to determine which of two palate surgeries and which timing of palate surgery were associated with better otologic and audiologic outcomes in children with unilateral cleft lip and palate at 5 to 6 years of age.
DESIGN: Subjects were randomly assigned to the von Langenbeck with intravelar veloplasty or Furlow palate repair, to palate surgery at 9 to 12 months or 15 to 18 months of age, and to the Spina or Millard lip repair.
SETTING: Centralized, tertiary care craniofacial treatment center.
PATIENTS: A total of 673 infants with unilateral cleft lip and palate.
INTERVENTIONS: Palate and lip were repaired using established techniques. Serial otoscopic and audiometric evaluations were performed.
MAIN OUTCOME MEASURES: Hearing and otoscopic findings at 5 to 6 years old.
RESULTS: There were 370 children available for analysis. Hearing and need for tympanostomy tube placement did not differ by palatoplasty, age at palatoplasty, cheiloplasty, or surgeon. Risk of developing cholesteatoma or perforation was higher with Millard cheiloplasty (odds ratio = 5.1, 95% confidence interval = 1.44 to 18.11, p = .012). Type and age at palatoplasty were not significantly associated with either the rate of developing these sequelae or the rate of achieving bilaterally normal hearing and ear examinations.
CONCLUSIONS: Type of palatoplasty did not influence otologic and audiologic outcomes in 5- to 6-year-olds with unilateral cleft lip and palate. The potential influence of lip repair on otologic outcomes warrants further investigation.
DESIGN: Subjects were randomly assigned to the von Langenbeck with intravelar veloplasty or Furlow palate repair, to palate surgery at 9 to 12 months or 15 to 18 months of age, and to the Spina or Millard lip repair.
SETTING: Centralized, tertiary care craniofacial treatment center.
PATIENTS: A total of 673 infants with unilateral cleft lip and palate.
INTERVENTIONS: Palate and lip were repaired using established techniques. Serial otoscopic and audiometric evaluations were performed.
MAIN OUTCOME MEASURES: Hearing and otoscopic findings at 5 to 6 years old.
RESULTS: There were 370 children available for analysis. Hearing and need for tympanostomy tube placement did not differ by palatoplasty, age at palatoplasty, cheiloplasty, or surgeon. Risk of developing cholesteatoma or perforation was higher with Millard cheiloplasty (odds ratio = 5.1, 95% confidence interval = 1.44 to 18.11, p = .012). Type and age at palatoplasty were not significantly associated with either the rate of developing these sequelae or the rate of achieving bilaterally normal hearing and ear examinations.
CONCLUSIONS: Type of palatoplasty did not influence otologic and audiologic outcomes in 5- to 6-year-olds with unilateral cleft lip and palate. The potential influence of lip repair on otologic outcomes warrants further investigation.
Предметные рубрики MeSH
Acoustic Impedance TestsAge FactorsAudiometry, Pure-ToneCholesteatoma, Middle EarCleft LipCleft PalateDouble-Blind MethodEar DiseasesEar, MiddleFemaleFollow-Up StudiesHearing LossHearing Loss, ConductiveHumansInfantMaleMiddle Ear VentilationOtitis Media with EffusionOtoscopyPalate, SoftProspective StudiesPlastic Surgery ProceduresTreatment OutcomeTympanic Membrane Perforation