International journal of pediatric otorhinolaryngology · 2009
A systematic review of concomitant interventions to prevent persistent perforations following the removal of long-term ventilation tubes.
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Keir J, Clarke R
Аннотация
OBJECTIVE: To review the current evidence for the use of concomitant interventions to reduce the persistent perforation rate following the removal of long-term ventilation tubes.
TYPE OF REVIEW: A systematic review of the literature and meta-analysis of randomised controlled trials on this topic.
SEARCH STRATEGY: Medline (1952-2008), EMBASE (1974-2008) and the Cochrane Central Register of Controlled Trials. A combination of search terms were used in a search strategy derived from guidance from the Cochrane collaboration.
EVALUATION METHOD: A review of all trials by two authors with grading of the level of evidence.
RESULTS: Fifteen studies using a variety of interventions were identified.
CONCLUSION: A multi-centre randomised controlled trial is indicated to validate findings of previous studies and elucidate any optimum intervention to reduce the persistent perforation rate.
TYPE OF REVIEW: A systematic review of the literature and meta-analysis of randomised controlled trials on this topic.
SEARCH STRATEGY: Medline (1952-2008), EMBASE (1974-2008) and the Cochrane Central Register of Controlled Trials. A combination of search terms were used in a search strategy derived from guidance from the Cochrane collaboration.
EVALUATION METHOD: A review of all trials by two authors with grading of the level of evidence.
RESULTS: Fifteen studies using a variety of interventions were identified.
CONCLUSION: A multi-centre randomised controlled trial is indicated to validate findings of previous studies and elucidate any optimum intervention to reduce the persistent perforation rate.