Role of Vitamin D and Vitamin D Receptor in Oral Lichen Planus: A Systematic Review.

BACKGROUND

Oral lichen planus (OLP) is known to be a chronic inflammatory disease associated with various other systemic disorders. Studies have shown that vitamin D deficiency can be involved in the pathogenesis of lichen planus. The aim of this study was to investigate the role of vitamin D and vitamin D receptor in OLP.

METHODS

In this review study, all English and Persian articles were searched by relevant keywords from the Google scholar, PubMed, science direct, Cochrane, Scopus and Sid databases until January 2020.

RESULTS

From the 16 articles obtained after reviewing the abstracts, finally 14 appropriate articles were included in this study.

CONCLUSION

According to the results of the studies, vitamin D deficiency may be associated with an increased risk of OLP lesions.