Kardiologia polska · 2026
Factors associated with quality of life in patients with heart failure and its impact on mortality.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Bednarek Adrian, Wojdyńska Zuzanna, Byczkowska Katarzyna, Kowalik Ilona, Drożdż Jarosław, Galas Agata, Tymińska Agata, Furman-Niedziejko Anna, Tkaczyszyn Michał, Stefański Adrian, Major Agnieszka, Klimczak-Tomaniak Dominika, Hamala Piotr, Zachura Małgorzata, Leszek Przemysław
Аннотация
BACKGROUND: In heart failure (HF), patients' quality of life (QoL) is influenced not only by cardiacfunction but also by coexisting conditions. Despite the widespread use of QoL assessments, therole of patient-related factors as determinants of QoL remains not fully elucidated.
AIMS: This study aims to assess the relative impact of different factors on QoL in HF patients, as well as its impact on mortality in this group.
METHODS: The study was based on the national registry - HEart failuRe ObsErvational Study of the Polish Cardiac Society, in which QoL was assessed at baseline (Kansas City CardiomyopathyQuestionnaire [KCCQ]-12), and follow-up data on all-cause mortality were obtained. Adjusted linearregression was used to identify factors associated with KCCQ-12.
RESULTS: The study included 1397 patients with a median KCCQ-12 score of 47.92 (28.65-72.92). Higher New York Heart Association class patients had consistently lower values of all KCCQ-12domains and KCCQ-12 overall scores (85 [69-93] vs. 65 [46-79] vs. 35 [23-49] vs. 21 [10-38]; allP <0.001). Hospitalized patients had significantly lower KCCQ-12 overall score, with a significantdifference between patients hospitalized for HF or non-cardiac reasons and patients hospitalizedfor other cardiac conditions. Apart from visit type, individual factors, cardiovascular conditions, andnon-cardiac conditions were independently associated with KCCQ-12. KCCQ-12 also significantlyinfluenced all-cause mortality (hazard ratio per 1 point increase = 0.976; 95% confidence interval,0.970-0.981; P <0.001).
CONCLUSIONS: Individual factors with both cardiac and non-cardiac comorbidities are independentlyassociated with QoL in patients with HF. The KCCQ-12 integrates all these factors and may serve asa simple, easily accessible tool for prognostic assessment.
AIMS: This study aims to assess the relative impact of different factors on QoL in HF patients, as well as its impact on mortality in this group.
METHODS: The study was based on the national registry - HEart failuRe ObsErvational Study of the Polish Cardiac Society, in which QoL was assessed at baseline (Kansas City CardiomyopathyQuestionnaire [KCCQ]-12), and follow-up data on all-cause mortality were obtained. Adjusted linearregression was used to identify factors associated with KCCQ-12.
RESULTS: The study included 1397 patients with a median KCCQ-12 score of 47.92 (28.65-72.92). Higher New York Heart Association class patients had consistently lower values of all KCCQ-12domains and KCCQ-12 overall scores (85 [69-93] vs. 65 [46-79] vs. 35 [23-49] vs. 21 [10-38]; allP <0.001). Hospitalized patients had significantly lower KCCQ-12 overall score, with a significantdifference between patients hospitalized for HF or non-cardiac reasons and patients hospitalizedfor other cardiac conditions. Apart from visit type, individual factors, cardiovascular conditions, andnon-cardiac conditions were independently associated with KCCQ-12. KCCQ-12 also significantlyinfluenced all-cause mortality (hazard ratio per 1 point increase = 0.976; 95% confidence interval,0.970-0.981; P <0.001).
CONCLUSIONS: Individual factors with both cardiac and non-cardiac comorbidities are independentlyassociated with QoL in patients with HF. The KCCQ-12 integrates all these factors and may serve asa simple, easily accessible tool for prognostic assessment.