Gender differences in outcomes among patients with heart failure and preserved ejection fraction: A retrospective cohort study.

Gender differences in the clinical presentation and outcomes of heart failure with preserved ejection fraction (HFpEF) remain inadequately characterized. This retrospective cohort study evaluated 146 HFpEF patients to compare baseline features and one-year outcomes between males and females. Female patients were more frequently obese or hypertensive, whereas male patients more often had coronary artery disease. Despite these differing risk profiles, females exhibited lower mortality and all-cause hospitalization rates at one year. These findings underscore meaningful gender-based variations in HFpEF and support the need for gender-sensitive strategies in clinical management and prognostication.