European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
Hennebert's sign due to intralabyrinthine schwannoma - case report.
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van de Berg Raymond, van Orsouw Milou, Szweryn Walter Jakub, Waterval Jérôme Joseph, Postma Alida Annechien, Kunst Henricus Petrus Maria, Stultiens Joost Johannes Antonius
Аннотация
OBJECTIVE: To illustrate how careful examination can reveal signs that may be elicited by an intralabyrinthine schwannoma.
PATIENTS: A patient referred to a tertiary dizziness referral clinic.
INTERVENTION(S): The patient underwent extensive vestibular assessment, audiometry, and imaging, including computed tomography (CT) and contrast-enhanced magnetic resonance imaging (MRI).
MAIN OUTCOME MEASURE(S): Signs of central or vestibular pathology were assessed, including the fistula test, as well as audiometric thresholds and imaging abnormalities.
RESULTS: The patient exhibited unilateral vestibular hypofunction and profound hearing loss in the left ear. Application of a Politzer balloon to the left external auditory canal induced a combination of upbeat nystagmus and horizontal nystagmus to the left, particularly upon pressure release. The CT scan showed no abnormalities. MRI revealed a schwannoma located in the basal and middle turns of the left cochlea extending into the vestibule and in close contact with the stapes.
CONCLUSIONS: This case report provides unique evidence of Hennebert’s sign in a patient with an intralabyrinthine schwannoma, highlighting the importance of performing detailed vestibular testing and considering this diagnosis.
SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00405-026-10238-4.
PATIENTS: A patient referred to a tertiary dizziness referral clinic.
INTERVENTION(S): The patient underwent extensive vestibular assessment, audiometry, and imaging, including computed tomography (CT) and contrast-enhanced magnetic resonance imaging (MRI).
MAIN OUTCOME MEASURE(S): Signs of central or vestibular pathology were assessed, including the fistula test, as well as audiometric thresholds and imaging abnormalities.
RESULTS: The patient exhibited unilateral vestibular hypofunction and profound hearing loss in the left ear. Application of a Politzer balloon to the left external auditory canal induced a combination of upbeat nystagmus and horizontal nystagmus to the left, particularly upon pressure release. The CT scan showed no abnormalities. MRI revealed a schwannoma located in the basal and middle turns of the left cochlea extending into the vestibule and in close contact with the stapes.
CONCLUSIONS: This case report provides unique evidence of Hennebert’s sign in a patient with an intralabyrinthine schwannoma, highlighting the importance of performing detailed vestibular testing and considering this diagnosis.
SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00405-026-10238-4.