Journal of medical case reports · 2009
Pityriasis rubra pilaris presenting with an abnormal autoimmune profile: two case reports.
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Gregoriou Stamatis, Chiolou Zoe, Stefanaki Christina, Zakopoulou Niki, Rigopoulos Dimitrios, Kontochristopoulos George
Аннотация
INTRODUCTION: Pityriasis rubra pilaris is an uncommon inflammatory and hyperproliferative dermatosis of juvenile or adult onset. The etiology of the disease is still unknown.
CASE PRESENTATION: We present the cases of two Caucasian men aged 53 and 48 who presented with pityriasis rubra pillaris type 1; both patients also exhibited an abnormal immunological profile.
CONCLUSION: Pityriasis rubra pillaris is currently classified as a keratinization disorder. The abnormal immunological profile reported in our patients along with the comorbidity of pityriasis rubra pilaris with autoimmune disorders reported in the literature poses the question of a possible pathogenetic role for the immune response in this disorder.
CASE PRESENTATION: We present the cases of two Caucasian men aged 53 and 48 who presented with pityriasis rubra pillaris type 1; both patients also exhibited an abnormal immunological profile.
CONCLUSION: Pityriasis rubra pillaris is currently classified as a keratinization disorder. The abnormal immunological profile reported in our patients along with the comorbidity of pityriasis rubra pilaris with autoimmune disorders reported in the literature poses the question of a possible pathogenetic role for the immune response in this disorder.