American journal of ophthalmology · 2006
Resolution of pityriasis rubra pilaris-induced cicatricial ectropion with systemic low-dose methotrexate.
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Durairaj Vikram D, Horsley Michael B
Аннотация
PURPOSE: To report a case of pityriasis rubra pilaris (PRP)-induced bilateral lower eyelid cicatricial ectropion that resolved with systemic low-dose methotrexate.
DESIGN: Observational case report.
METHODS: A retrospective case review of a patient with cicatricial ectropion caused by PRP.
RESULTS: A 82-year-old female presented with bilateral lower eyelid cicatricial ectropion secondary to PRP. The patient did not systemically respond to conventional oral retinoid therapy. She was treated with low-dose methotrexate and experienced dramatic resolution of her signs and symptoms, including complete resolution of her bilateral cicatricial ectropion.
CONCLUSION: Systemic treatment of PRP with low-dose methotrexate may result in successful treatment of cicatricial ectropion without surgery.
DESIGN: Observational case report.
METHODS: A retrospective case review of a patient with cicatricial ectropion caused by PRP.
RESULTS: A 82-year-old female presented with bilateral lower eyelid cicatricial ectropion secondary to PRP. The patient did not systemically respond to conventional oral retinoid therapy. She was treated with low-dose methotrexate and experienced dramatic resolution of her signs and symptoms, including complete resolution of her bilateral cicatricial ectropion.
CONCLUSION: Systemic treatment of PRP with low-dose methotrexate may result in successful treatment of cicatricial ectropion without surgery.