European journal of ophthalmology · 2018
Laminar drainage implant.
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Jacobovitz Sergio, Massote José Aloísio, Cronemberger Sebastião
Аннотация
OBJECTIVE: To assess the feasibility of a novel surgical technique in painful blind eyes.
DESIGN: A prospective safety study conducted at the Federal University of Minas Gerais, Brazil.
PARTICIPANTS/SAMPLES: A total of 15 end-stage glaucomatous eyes without light perception vision.
METHODS: After implantation, conjunctival hyperemia, discharge, erosion, aqueous humor leakage, corneal edema, hyphema, anterior chamber cells and depth, dislocation of the implant, and filtering bleb height were assessed by slit-lamp biomicroscopy. Intraocular pressure was measured preoperatively and 24 months following surgery. A numerical rating scale was used to evaluate pain. Anterior segment optical coherence tomography was also assessed.
RESULTS: Laminar drainage implant surgery was performed in all patients without major complications. Mean intraocular pressure was significantly reduced after surgery without hypotensive medication (preoperatively 54.5 ± 5.1 mmHg vs 24 months after surgery 37.0 ± 15.4 mmHg, p = 0.003). Subjective ocular pain intensity also reduced (preoperatively 10 vs at 24-month follow-up visits 0). Corneal edema incidence reduced from 85.7% (95% confidence interval: 57.2%-98.2%) to 16.7% (95% confidence interval: 2.1%-48.4%) at the 24-month follow-up. No patients experienced a prolonged flat anterior chamber or erosion of overlying tissues.
CONCLUSION: The surgery was feasible and safe in painful blind eyes.
DESIGN: A prospective safety study conducted at the Federal University of Minas Gerais, Brazil.
PARTICIPANTS/SAMPLES: A total of 15 end-stage glaucomatous eyes without light perception vision.
METHODS: After implantation, conjunctival hyperemia, discharge, erosion, aqueous humor leakage, corneal edema, hyphema, anterior chamber cells and depth, dislocation of the implant, and filtering bleb height were assessed by slit-lamp biomicroscopy. Intraocular pressure was measured preoperatively and 24 months following surgery. A numerical rating scale was used to evaluate pain. Anterior segment optical coherence tomography was also assessed.
RESULTS: Laminar drainage implant surgery was performed in all patients without major complications. Mean intraocular pressure was significantly reduced after surgery without hypotensive medication (preoperatively 54.5 ± 5.1 mmHg vs 24 months after surgery 37.0 ± 15.4 mmHg, p = 0.003). Subjective ocular pain intensity also reduced (preoperatively 10 vs at 24-month follow-up visits 0). Corneal edema incidence reduced from 85.7% (95% confidence interval: 57.2%-98.2%) to 16.7% (95% confidence interval: 2.1%-48.4%) at the 24-month follow-up. No patients experienced a prolonged flat anterior chamber or erosion of overlying tissues.
CONCLUSION: The surgery was feasible and safe in painful blind eyes.
Предметные рубрики MeSH
AdultAgedAged, 80 and overAnterior ChamberAqueous HumorBlindnessCorneal EdemaEye PainFeasibility StudiesFemaleGlaucomaGlaucoma Drainage ImplantsHumansIntraocular PressureMaleMiddle AgedPostoperative ComplicationsProspective StudiesProsthesis ImplantationTomography, Optical CoherenceTonometry, Ocular