A novel lanthanide metal-organic framework hydrogel for "turn-on" sensing of norfloxacin antibiotics in carassius auratu and milk.

Utilizing the "turn-on" emission sensing mode, the sensor platform for norfloxacin (NOR) detection was developed by utilizing the lanthanide metal-organic framework, Eu-MOF. The Eu-MOF exhibits high specificity and anti-resistance to interference in cognizing recognition of NOR. The results show that the Eu-MOF exhibits high efficacy and precision in norfloxacin detection, with a fluorescence detection limit of 0.56 μM. Additionally, a visual detection "turn-on" emission platform, Eu-MOF@PVA/SA, was successfully established to facilitate the detection of NOR. This platform utilizes a smartphone, an Eu-MOF, and PVA/SA hydrogel, with a detection limit of 1.87 μM for visual detection. Excellent NOR detection capabilities were shown by both Eu-MOF and Eu-MOF@PVA/SA in real carassius auratus and milk samples. Consequently, this strategy offers a promising approach to the straightforward and precise determination of NOR.