Journal of cutaneous medicine and surgery · 2014
Atypical fibroxanthoma arising in a scar of discoid lupus erythematosus.
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De Francesco Vincenzo, Errichetti Enzo, Pegolo Enrico, Stinco Giuseppe
Аннотация
BACKGROUND: Malignant change in the scars of discoid lupus erythematosus (DLE) is a well-known event. In most cases, tumors are of epithelial origin, particularly squamous cell carcinomas and, less frequently, basal cell carcinomas and keratoacanthomas. The onset of soft tissue sarcomas in a DLE scar is a very rare event, however, because only one case of malignant fibrous histiocytoma has been described in the literature.
OBJECTIVE: We describe the first documented report of atypical fibroxanthoma (AFX) arising in an old scar of DLE.
RESULTS: Although we cannot exclude an accidental association between AFX and DLE, our case emphasizes that patients with DLE may develop AFX in the context of an old scar.
CONCLUSION: Our finding further underlines the importance of strict and long-term surveillance of people with DLE to identify and remove eventual tumors at an early stage.
OBJECTIVE: We describe the first documented report of atypical fibroxanthoma (AFX) arising in an old scar of DLE.
RESULTS: Although we cannot exclude an accidental association between AFX and DLE, our case emphasizes that patients with DLE may develop AFX in the context of an old scar.
CONCLUSION: Our finding further underlines the importance of strict and long-term surveillance of people with DLE to identify and remove eventual tumors at an early stage.