Allergologie select · 2025
Hymenoptera venom allergy: How negative testing after five years of immunotherapy informs treatment discontinuation.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Cavara Matteo, Botta Alice, Chiei Gallo Alessandra, Bono Eleonora, Ratti Christian P, Iemoli Enrico, Ortolani Valeria G R
Аннотация
BACKGROUND: Hymenoptera venom allergy represents a potentially life-threatening condition. Venom immunotherapy (VIT) is the treatment of choice in patients with systemic reactions.
CASE PRESENTATION: We report the case of a 65-year-old male, who experienced systemic reactions following hymenoptera stings. In vitro and in vivo allergy tests revealed sensitization predominantly to Polistes dominula and specific VIT was initiated. During VIT, the patient experienced two subsequent stings with only local reactions. After 5 years of VIT, repeated serological evaluation and skin tests turned negative, leading to the decision to discontinue therapy.
CONCLUSION: This case underlines the efficacy and safety of VIT in patients with severe hymenoptera venom allergy in preventing systemic reactions. A comprehensive diagnostic work-up, including laboratory and skin tests, is crucial in the management and subsequent evaluation of therapeutic efficacy.
CASE PRESENTATION: We report the case of a 65-year-old male, who experienced systemic reactions following hymenoptera stings. In vitro and in vivo allergy tests revealed sensitization predominantly to Polistes dominula and specific VIT was initiated. During VIT, the patient experienced two subsequent stings with only local reactions. After 5 years of VIT, repeated serological evaluation and skin tests turned negative, leading to the decision to discontinue therapy.
CONCLUSION: This case underlines the efficacy and safety of VIT in patients with severe hymenoptera venom allergy in preventing systemic reactions. A comprehensive diagnostic work-up, including laboratory and skin tests, is crucial in the management and subsequent evaluation of therapeutic efficacy.