Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2016
Descemet stripping automated endothelial keratoplasty using corneas from elderly donors.
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Nakatani Satoru, Murakami Akira
Аннотация
PURPOSE: To evaluate the outcomes of Descemet stripping automated endothelial keratoplasty (DSAEK) using corneas from elderly donors.
METHODS: A total of 90 eyes that underwent DSAEK at Juntendo University Hospital between January 2008 and December 2012 were divided into two groups. Group 1 was eyes that received corneas from elderly donors aged 80 years or older (29 eyes), and group 2 was eyes that received corneas from donors aged 79 years or younger (61 eyes). Patient characteristics and visual acuity, endothelial cell density, and postoperative complications at 2 years after surgery were examined retrospectively.
RESULTS: The mean age of the donors was 86.3 ± 28.9 years (range, 80-98 years) in group 1 and 62.1 ± 23.2 years (range, 26-79 years) in group 2. At 2 years after surgery, median logMAR visual acuity was 0.48 ± 0.38 in group 1 and 0.42 ± 0.47 in group 2, while the median loss of endothelial cell density was 38.9 ± 22.5 % and 39.7 ± 23.8 %, respectively. There was no significant difference between the two groups for all the parameters.
CONCLUSIONS: The rate of endothelial cell loss at 2 years after surgery was similar regardless of donor age (≥80 years vs ≤79 years). It seems reasonable to use corneas from donors aged 80 years or older for DSAEK provided the selection criteria are fulfilled.
METHODS: A total of 90 eyes that underwent DSAEK at Juntendo University Hospital between January 2008 and December 2012 were divided into two groups. Group 1 was eyes that received corneas from elderly donors aged 80 years or older (29 eyes), and group 2 was eyes that received corneas from donors aged 79 years or younger (61 eyes). Patient characteristics and visual acuity, endothelial cell density, and postoperative complications at 2 years after surgery were examined retrospectively.
RESULTS: The mean age of the donors was 86.3 ± 28.9 years (range, 80-98 years) in group 1 and 62.1 ± 23.2 years (range, 26-79 years) in group 2. At 2 years after surgery, median logMAR visual acuity was 0.48 ± 0.38 in group 1 and 0.42 ± 0.47 in group 2, while the median loss of endothelial cell density was 38.9 ± 22.5 % and 39.7 ± 23.8 %, respectively. There was no significant difference between the two groups for all the parameters.
CONCLUSIONS: The rate of endothelial cell loss at 2 years after surgery was similar regardless of donor age (≥80 years vs ≤79 years). It seems reasonable to use corneas from donors aged 80 years or older for DSAEK provided the selection criteria are fulfilled.
Предметные рубрики MeSH
AdultAge FactorsAgedAged, 80 and overCell CountCorneaCorneal DiseasesCorneal Endothelial Cell LossDescemet Stripping Endothelial KeratoplastyDonor SelectionEndothelium, CornealEye BanksFemaleGraft SurvivalHumansMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesTissue DonorsVisual Acuity