American journal of ophthalmology case reports · 2025
Two cases of therapeutic scleral lenses for KID syndrome.
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Gagliardi Melynda, Asghari Bita
Аннотация
PURPOSE: This case series describes the therapeutic application of customized scleral lenses via prosthetic replacement of the ocular surface ecosystem (PROSE) in patients with Keratitis-Ichthyosis-Deafness (KID) syndrome. It proposes PROSE or scleral lens wear as a therapeutic option for KID syndrome.
OBSERVATIONS: Two patients with KID syndrome were successfully fitted with PROSE devices, also referred to as prosthetic devices, and continued with wear. The duration of lens wear ranged from one to seven years. One patient was pediatric with severe disease, and the other an adult with milder disease. The pediatric patient had challenges with application and removal and ultimately discontinued device wear; however, demonstrated improvement in corneal surface health through duration of wear for the right eye. The second patient continued with device wear for seven years, with resolution of recurrent corneal erosions, improved comfort and stabilization of corneal surface health. Both patients had benefit with PROSE device wear.
CONCLUSION AND IMPORTANCE: Management of ocular surface disease in KID syndrome can be challenging with limited therapeutic options including poor surgical outcomes. This case series supports the therapeutic application of scleral lenses in patients with KID syndrome.
OBSERVATIONS: Two patients with KID syndrome were successfully fitted with PROSE devices, also referred to as prosthetic devices, and continued with wear. The duration of lens wear ranged from one to seven years. One patient was pediatric with severe disease, and the other an adult with milder disease. The pediatric patient had challenges with application and removal and ultimately discontinued device wear; however, demonstrated improvement in corneal surface health through duration of wear for the right eye. The second patient continued with device wear for seven years, with resolution of recurrent corneal erosions, improved comfort and stabilization of corneal surface health. Both patients had benefit with PROSE device wear.
CONCLUSION AND IMPORTANCE: Management of ocular surface disease in KID syndrome can be challenging with limited therapeutic options including poor surgical outcomes. This case series supports the therapeutic application of scleral lenses in patients with KID syndrome.