Psychotic Onset During the Second Trimester of Pregnancy: A Case Report and Review of the Literature.

The manuscript presents a case of a 29-year-old pregnant woman who developed a severe psychotic episode during the second trimester of her pregnancy. Bipolar disorder (BD) is a serious mood disorder of uncertain etiology marked by significant and long-lasting fluctuations in mood. It is a major cause of disability worldwide, with a higher rate of progression and frequency in women. Pregnancy represents a vulnerable period for women with BD, as hormonal and psychological changes can trigger severe mood episodes. Pharmacological treatment was given, and her pregnancy was closely monitored. A cesarean section was performed at 36 weeks, and postpartum medication adjustments were made. At six months follow-up, the patient showed signs of symptom remission, though she required subsequent psychiatric care.