Journal of pharmacy & bioallied sciences · 2025
Eggshell Derived Nanohydroxyapatite as a Bone Graft for Intrabony Defects was Evaluated Using (CBCT) - A Randomized Controlled Trial.
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Ganapathy Vishnuvarthan, Balaji Anitha, Kumar T S Sampath, Shanmugam Mohanasatheesh
Аннотация
AIM: The study aims to assess the effectiveness of eggshell-derived nanohydroxyapatite (EnHA) as a bone graft material for treating intrabony defects, using cone-beam computed tomography (CBCT) for evaluation.
MATERIALS AND METHODS: Ten patients were divided into two groups: Group 1: individuals with 2-wall defects, Group 2: those with 3-wall defects. Follow-up appointments at 1-, 3-, and 6-month intervals included assessments of clinical attachment level (CAL), probing depth (PD), and gingival recession (GR). CBCT scans were conducted pre-operative, immediately post-surgery, and at 1-month, 3-month, and 5-month follow-ups.
RESULTS: In both groups, clinical parameters such as CAL, PD, and CBCT measurements reveal significant decreases in CAL and PD values alongside positive trends in CBCT measurements. Additionally, Group 2 exhibited enhancements in periodontal health, suggesting the potential effectiveness of EnHA.
CONCLUSION: EnHA demonstrates potential as a substitute for bone grafting in intrabony defects, showing favourable trends in both clinical and CBCT evaluations during a 6-month observation period.
MATERIALS AND METHODS: Ten patients were divided into two groups: Group 1: individuals with 2-wall defects, Group 2: those with 3-wall defects. Follow-up appointments at 1-, 3-, and 6-month intervals included assessments of clinical attachment level (CAL), probing depth (PD), and gingival recession (GR). CBCT scans were conducted pre-operative, immediately post-surgery, and at 1-month, 3-month, and 5-month follow-ups.
RESULTS: In both groups, clinical parameters such as CAL, PD, and CBCT measurements reveal significant decreases in CAL and PD values alongside positive trends in CBCT measurements. Additionally, Group 2 exhibited enhancements in periodontal health, suggesting the potential effectiveness of EnHA.
CONCLUSION: EnHA demonstrates potential as a substitute for bone grafting in intrabony defects, showing favourable trends in both clinical and CBCT evaluations during a 6-month observation period.