Clinical biochemistry · 2005
Reliability of quantitative and qualitative tests to identify heterozygotes carrying severe or mild G6PD deficiency.
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Tagarelli Antonio, Piro Anna, Bastone Loredana, Condino Francesca, Tagarelli Giuseppe
Аннотация
OBJECTIVES: To determine if the qualitative test (cytochemical) is more reliable than the quantitative test (differential pH-metry) in identifying heterozygous G6PD- subjects.
DESIGN AND METHODS: Identification of heterozygous G6PD- subjects was done by the measurement of G6PD activity and by a cytochemical test.
RESULTS: A cytochemical test is more sensitive than differential pH-metry to identify heterozygous G6PD- subjects.
CONCLUSIONS: A cytochemical test is a reliable method for mass screening for G6PD deficiency to identify G6PD- heterozygotes.
DESIGN AND METHODS: Identification of heterozygous G6PD- subjects was done by the measurement of G6PD activity and by a cytochemical test.
RESULTS: A cytochemical test is more sensitive than differential pH-metry to identify heterozygous G6PD- subjects.
CONCLUSIONS: A cytochemical test is a reliable method for mass screening for G6PD deficiency to identify G6PD- heterozygotes.