Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2024
Technical recommendations for implementation of Volumetric Modulated Arc Therapy and Helical Tomotherapy Total Body Irradiation.
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Seravalli Enrica, Bosman Mirjam E, Han Chunhui, Losert Christoph, Pazos Montserrat, Engström Per E, Engellau Jacob, Fulcheri Christian P L, Zucchetti Claudio, Saldi Simonetta, Ferrer Carlos, Ocanto Abrahams, Hiniker Susan M, Clark Catharine H, Hussein Mohammad, Misson-Yates Sarah, Kobyzeva Daria A, Loginova Anna A, Hoeben Bianca A W
Аннотация
As a component of myeloablative conditioning before allogeneic hematopoietic stem cell transplantation (HSCT), Total Body Irradiation (TBI) is employed in radiotherapy centers all over the world. In recent and coming years, many centers are changing their technical setup from a conventional TBI technique to multi-isocenter conformal arc therapy techniques such as Volumetric Modulated Arc Therapy (VMAT) or Helical Tomotherapy (HT). These techniques allow better homogeneity and control of the target prescription dose, and provide more freedom for individualized organ-at-risk sparing. The technical design of multi-isocenter/multi-plan conformal TBI is complex and should be developed carefully. A group of early adopters with conformal TBI experience using different treatment machines and treatment planning systems came together to develop technical recommendations and share experiences, in order to assist departments wishing to implement conformal TBI, and to provide ideas for standardization of practices.