Acta otorrinolaringologica espanola · 1994
[Results of radiotherapy in 117 cases of carcinoma of pyriform sinuses].
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Ramos Fernández J, Avilés Mañoso P, Martín Atienza R, Lozano Barriuso M A, Fernández-Vega M
Аннотация
A retrospective study was made of 117 cases of squamous cell carcinoma of the pyriform sinus treated with radiation therapy (RTX). Sixty-three patients underwent radical RTX (group I) and 54 patients received combined treatment (group II). Adjuvant chemotherapy (QTX) was applied in 36 patients (27 of group I, 9 of group II). Residual disease after treatment was observed in 35% (group I) and 4% (group II) (p < 0.001). The rates of local and/or regional recurrence were 46% and 38% respectively. Distant metastases were found in 6% (group I) and 20% (group II) (p < 0.05). The 5-year actuarial survival rates were 23% (group I) and 35% (group II). The group I patients who received QTX had better survival rates (41%) than those who did not (13%) (p < 0.05). The group II survival was not improved by QTX.