Prognostic factors in pyriform sinus carcinoma.

In the 48-month survival analysis of 76 evaluable pyriform sinus carcinoma cases, nodal stage and size played the most significant prognosis-affecting roles. N3 stage and node greater than 3 cm decreased the survival fourfold and threefold, respectively, at statistically significant levels. The difference between the 35 per cent preoperative radiation therapy and 3 per cent radical radiation therapy cumulative 48-mouth survivals was significant at p less than 0.01. Complication rates were 6 per cent with radical radiation, 35 per cent with preoperative radiation and 43 per cent with curative surgery.