Revista iberoamericana de micologia · 2010
Sudden blindness due to bilateral optic neuropathy associated with cryptococcal meningitis in an AIDS patient.
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Corti Marcelo, Solari Rubén, Cangelosi Diana, Domínguez Cecilia, Yampolsky Claudio, Negroni Ricardo, Arechavala Alicia, Schtirbu Ricardo
Аннотация
BACKGROUND: Cryptococcosis is one of the most frequent and severe AIDS defining illnesses.
AIMS: We present a patient with advanced HIV/AIDS disease and a diffuse meningoencephalitis due to Cryptococcus neoformans. The patient developed an acute and bilateral blindness associated with high cerebrospinal fluid pressure and optic neuropathy.
METHODS: Post-mortem anatomopathologic study revealed a high number of Cryptococcus in the central nervous system, including the optic nerves and the optic chiasm.
CONCLUSION: The patient's sudden visual loss appeared to be related to the perineuritic arachnoiditis and the massive invasion of the optic nerves by the fungus.
AIMS: We present a patient with advanced HIV/AIDS disease and a diffuse meningoencephalitis due to Cryptococcus neoformans. The patient developed an acute and bilateral blindness associated with high cerebrospinal fluid pressure and optic neuropathy.
METHODS: Post-mortem anatomopathologic study revealed a high number of Cryptococcus in the central nervous system, including the optic nerves and the optic chiasm.
CONCLUSION: The patient's sudden visual loss appeared to be related to the perineuritic arachnoiditis and the massive invasion of the optic nerves by the fungus.