[Mechanisms underlying the antimicrobial and immunomodulatory activities of porcine antimicrobial peptides].

Porcine antimicrobial peptides (AMPs) possess excellent antimicrobial activities and multiple biological functions, playing an essential role in the host's innate immune defense against pathogen infections. With the growing limitations of antibiotics, AMPs have been extensively studied due to their mild drug resistance and potent immunomodulatory activities. Porcine AMPs as vital components in the host defense against pathogen infections have the potential to be developed as anti-infective drugs. This review focused on the research progress in porcine AMPs regarding the structure-activity relationships and the antimicrobial and immunomodulatory activities, and discussed the potential application prospects, providing a basis for the development of anti-infective drugs in veterinary medicine.