Correlation between healthy sleep score and risk of cardia-cerebrovascular disease among people with type 2 diabetes: a prospective cohort study.

BACKGROUND

In the general population, healthy sleep pattern is associated with lower risk of cardia-cerebrovascular diseases (CVD). However, despite a high prevalence of sleep disorders in people type 2 diabetes(T2D), no study has investigated the relationship between sleep patterns and the risk of CVD events in this particular subpopulation.

METHODS

We included 6,363 participants with T2D but free of prevalent CVD at baseline from Kailuan study, a HSS(range 0-5) combining five sleep patterns (sleep duration, snoring, insomnia, early sleep-wake patterns, and excessive daytime sleepiness) was calculated. Cox regression models were used to evaluate the hazard ratios (HRs) and 95% confidence intervals (CIs) of incident CVD.

RESULTS

During a median follow-up of 5.80 years, 790 participants developed first CVD event (12.42%). In multivariate Cox analysis, the risk of CVD decreased by 11% (HR, 0.89; 95% CI 0.83-0.96) per one-point increment in the HSS. Compared to those with a sleep score of 0-1, participants with a score of 4 and 5 had a 26%(HR, 0.73; 95% CI 0.55-0.99) and 43%(HR, 0.58; 95% CI 0.35-0.93) reduced risk of CVD, respectively.

CONCLUSION

Higher HSS are associated with a lower risk of CVD events in the community people with T2D.