JPEN. Journal of parenteral and enteral nutrition · 2004
Effects of enteral feeding on antroduodenal motility in healthy volunteers with 2 different fiber-supplemented diets: a 24-hour manometric study.
Клиническое исследованиеСтатьяРандомизированное исследованиеНазвание и аннотация: Перевод пока не подготовлен
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Bouin Mickael, Sassi Amel, Savoye Guillaume, Denis Philippe, Ducrotté Philippe
Аннотация
BACKGROUND: Antroduodenal motility during enteral nutrition remains poorly understood. The aim of the study was to evaluate antroduodenal motor activity during intermittent intragastric feeding and between enteral solutions supplemented with new recommended soluble or standard insoluble fibers.
METHODS: Two 24-hour antroduodenal manometric studies were performed with a interval of 1 week in 8 healthy volunteers. Two similar enteral diets except for fiber (soluble vs insoluble) were separately assessed in random order at 2 intervals (lunch and dinner) for 2 hours each. Phase III was studied during three 6 hour-periods (after lunch, after dinner, and at night). The other quantitative manometric parameters were studied before (1 hour), during (2 hours), and after (2 hours) lunch and dinner.
RESULTS: During the 2-hour postinfusion period, phase III reoccurred in 14 cases during the day and in 16 cases during the night. Phase III was always interrupted during feeding, which reoccurred in 14 cases during the 2-hour postinfusion period and in 16 cases during the after-dinner period. Nocturnal phase III was more frequent, lasted longer, with a lower amplitude than the diurnal phase. Addition of either soluble or insoluble fiber did not appear to have an influence on phase III or on the antroduodenal motor activity.
CONCLUSIONS: Intragastric feeding interrupted phase III at the antroduodenal stage during infusion but was correlated with interdigestive motility. Antroduodenal motility did not significantly change either during or after intragastric feeding. The addition of either soluble or insoluble fiber does not seem to have an influence on gastroduodenal motor response to intermittent intragastric feeding.
METHODS: Two 24-hour antroduodenal manometric studies were performed with a interval of 1 week in 8 healthy volunteers. Two similar enteral diets except for fiber (soluble vs insoluble) were separately assessed in random order at 2 intervals (lunch and dinner) for 2 hours each. Phase III was studied during three 6 hour-periods (after lunch, after dinner, and at night). The other quantitative manometric parameters were studied before (1 hour), during (2 hours), and after (2 hours) lunch and dinner.
RESULTS: During the 2-hour postinfusion period, phase III reoccurred in 14 cases during the day and in 16 cases during the night. Phase III was always interrupted during feeding, which reoccurred in 14 cases during the 2-hour postinfusion period and in 16 cases during the after-dinner period. Nocturnal phase III was more frequent, lasted longer, with a lower amplitude than the diurnal phase. Addition of either soluble or insoluble fiber did not appear to have an influence on phase III or on the antroduodenal motor activity.
CONCLUSIONS: Intragastric feeding interrupted phase III at the antroduodenal stage during infusion but was correlated with interdigestive motility. Antroduodenal motility did not significantly change either during or after intragastric feeding. The addition of either soluble or insoluble fiber does not seem to have an influence on gastroduodenal motor response to intermittent intragastric feeding.