Journal of cataract and refractive surgery · 2026
Intrastromal corneal ring segments in previously cross-linked vs virgin keratoconic corneas: multiparameter propensity score-matched analysis.
СтатьяСравнительное исследованиеНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
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Kozhaya Karim, Assaf Jad F, El Salloukh Nasrine Anais, Nasser Nour, Awwad Shady T
Аннотация
PURPOSE: To compare outcomes of intrastromal corneal ring segments (ICRS) insertion in crosslinked (CXL) vs non-CXL keratoconic eyes, using a multiparameter propensity score matching (PSM).
SETTING: American University of Beirut Medical Center, Beirut, Lebanon.
DESIGN: Retrospective case series.
METHODS: 198 eyes with mild to moderate keratoconus who underwent ICRS insertion were included. Our data were divided into 2 groups, based on whether CXL was performed before ICRS insertion. A PSM was used to balance the following covariates: age, sex, ICRS segment thickness, arc size, optical zone, topographic data, and total corneal coma. Visual, refractive, topographic, and total corneal aberrometric data were measured preoperatively and at 6-month post-ICRS implantation.
RESULTS: After 1:1 PSM, 32 eyes from 27 patients with prior CXL were matched to 32 untreated eyes from 30 patients. Preoperative parameters were not statistically different between the groups ( P s > .05). Both groups displayed a statistically significant improvement in visual, refractive, topographic (simulated keratometry, maximum axial keratometry, and keratometric astigmatism) and total corneal aberrometric (total higher-order aberrations and coma) outcomes 6 months after ICRS insertion (all P s < .05). The changes in all reported visual, refractive, topographic, and total corneal aberrometric outcomes were not statistically different between CXL and non-CXL eyes (all P s > .05).
CONCLUSIONS: When properly matched for preoperative disease type and severity, ICRS insertion had a similar improvement in eyes with and without CXL.
SETTING: American University of Beirut Medical Center, Beirut, Lebanon.
DESIGN: Retrospective case series.
METHODS: 198 eyes with mild to moderate keratoconus who underwent ICRS insertion were included. Our data were divided into 2 groups, based on whether CXL was performed before ICRS insertion. A PSM was used to balance the following covariates: age, sex, ICRS segment thickness, arc size, optical zone, topographic data, and total corneal coma. Visual, refractive, topographic, and total corneal aberrometric data were measured preoperatively and at 6-month post-ICRS implantation.
RESULTS: After 1:1 PSM, 32 eyes from 27 patients with prior CXL were matched to 32 untreated eyes from 30 patients. Preoperative parameters were not statistically different between the groups ( P s > .05). Both groups displayed a statistically significant improvement in visual, refractive, topographic (simulated keratometry, maximum axial keratometry, and keratometric astigmatism) and total corneal aberrometric (total higher-order aberrations and coma) outcomes 6 months after ICRS insertion (all P s < .05). The changes in all reported visual, refractive, topographic, and total corneal aberrometric outcomes were not statistically different between CXL and non-CXL eyes (all P s > .05).
CONCLUSIONS: When properly matched for preoperative disease type and severity, ICRS insertion had a similar improvement in eyes with and without CXL.