Unraveling the immune axis of ocular surface microbiota in keratoconus.

PURPOSE OF REVIEW: This review's objective is to give readers an update on recent and developing information about the function of the ocular surface microbiome in keratoconus.

RECENT FINDINGS: The microbiome's function in the pathogenesis of keratoconus is supported by recent research. Numerous metabolites that are produced by the ocular surface bacteria can affect the host tissue. A shift in the microbiota may influence the composition of these metabolites, which could have an effect on keratoconus by altering the cornea's metabolic environment.

SUMMARY: Gaining insight into the function of the ocular surface microbiota in keratoconus could open up new avenues for the creation of new therapeutic modalities.