[On diagnosis and prophylaxis of asthenoneurotic syndrome in cosmonauts in long-term mission].

Based on longer than 20 years experience of observation and investigation of the neuropsychic state of cosmonauts in long-term missions to the space stations and volunteers in ground studies of some of the spaceflight (SF) effects, principles of diagnostics, prophylaxis and correction of asthenoneurotic and psychoasthenic disorders in members of long-term orbital mission have been established. The authors give consideration to the most probable pathophysiological mechanisms of these disorders during SF and some potential lines of exploration and development of countermeasures against and methods for correction of the psychoneurologic disorders during long-term missions.