Internal medicine (Tokyo, Japan) · 1997
Idiopathic CD4+ T-lymphocytopenia in a non-Hodgkin's lymphoma patient.
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Hanamura I, Wakita A, Harada S, Tsuboi K, Komatsu H, Banno S, Iwaki O, Takeuchi G, Nitta M, Ueda R
Аннотация
We report a case of idiopathic CD4+ T-lymphocytopenia with malignant lymphoma (diffuse large, B-cell type) for which there was no evidence of human immunodeficiency virus type 1 or type 2 infection and no other known causes of immunodeficiency. She had never suffered from any opportunistic infection until the diagnosis of malignant lymphoma was made, and the CD4+ T-lymphocytopenia persisted after complete remission of the lymphoma. As the clinical features and immune status of the patient differed from those associated with the acquired immunodeficiency syndrome (AIDS)-related syndrome, we conclude that immunodeficiency in this case did not contribute to the opportunistic infection but may have been associated with the genesis of malignant lymphoma.