The Journal of otolaryngology · 2002
Can electrocochleography in Meniere's disease be noninvasive?
Клиническое исследованиеСравнительное исследованиеКонтролируемое клиническое исследованиеОценочное исследованиеСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Ghosh Shakuntala, Gupta Ashok K, Mann Sherbaaz Singh
Аннотация
OBJECTIVES: To evaluate and compare the results of extratympanic and transtympanic electrocochleography (ECochg) in clinically diagnosed cases of Meniere's disease and controls.
DESIGN: Prospective study on 20 clinically diagnosed cases of Meniere's disease and 20 age- and sex-matched controls.
SETTING: Department of Otolaryngology, Head and Neck Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
METHODS: Electrocochleography was performed by a transtympanic method using a stainless steel needle electrode kept on the promontory and by an extratympanic method whereby the needle electrode was inserted into bony canal skin.
MAIN OUTCOME MEASURES: The various parameters compared were summation potential latency and amplitude, action potential latency and amplitude, and ratio of summation to action potential amplitude (SP/AP).
RESULTS: A significant difference in summation to action potential amplitude ratio (SP/AP) between cases and controls was obtained by both methods. Using 0.29 as a cutoff for SP/AP, the transtympanic method yielded a sensitivity of 100% and a specificity of 90%, whereas the extratympanic method showed corresponding values of 90% and 80%, respectively.
CONCLUSION: Contrary to previous studies, extratympanic ECochg is shown to be an efficacious and a less invasive test as compared with the transtympanic method and can be easily performed in clinical practice.
DESIGN: Prospective study on 20 clinically diagnosed cases of Meniere's disease and 20 age- and sex-matched controls.
SETTING: Department of Otolaryngology, Head and Neck Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
METHODS: Electrocochleography was performed by a transtympanic method using a stainless steel needle electrode kept on the promontory and by an extratympanic method whereby the needle electrode was inserted into bony canal skin.
MAIN OUTCOME MEASURES: The various parameters compared were summation potential latency and amplitude, action potential latency and amplitude, and ratio of summation to action potential amplitude (SP/AP).
RESULTS: A significant difference in summation to action potential amplitude ratio (SP/AP) between cases and controls was obtained by both methods. Using 0.29 as a cutoff for SP/AP, the transtympanic method yielded a sensitivity of 100% and a specificity of 90%, whereas the extratympanic method showed corresponding values of 90% and 80%, respectively.
CONCLUSION: Contrary to previous studies, extratympanic ECochg is shown to be an efficacious and a less invasive test as compared with the transtympanic method and can be easily performed in clinical practice.