Hand, Foot, and Mouth Disease in a Patient With Psoriasis: A Case Report.

Hand, foot, and mouth disease (HFMD) is a viral infection commonly found in children but rare in adults. Patients with chronic skin conditions may worsen after an inoculation with an infectious agent with cutaneous tropism. The present case reports a 48-year-old male patient with a history of plaque psoriasis, with no identifiable epidemiological contacts, who presented at a primary health care consultation with painful vesicles, blisters, and pustules in the perioral region, elbows, hands, and soles of the feet. He was also observed in the hospital emergency department, where blood tests confirmed an enterovirus A71 infection. The patient was subsequently followed up in a dermatology consultation. This case report emphasizes the need for health professionals to consider HFMD in adults with unexplained cutaneous lesions with oral symptoms, especially when chronic dermatological diseases are present, due to the risk of their worsening.